Bioavailability of components of resin-based materials which are applied to teeth.
Identifieur interne : 000596 ( Main/Exploration ); précédent : 000595; suivant : 000597Bioavailability of components of resin-based materials which are applied to teeth.
Auteurs : W R Hume [États-Unis] ; T M GerzinaSource :
- Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists [ 1045-4411 ] ; 1996.
Descripteurs français
- KwdFr :
- Biodisponibilité (MeSH), Ciments dentaires (pharmacocinétique), Dent (MeSH), Dentine (métabolisme), Dentistes (MeSH), Dermatite professionnelle (étiologie), Eczéma de contact allergique (étiologie), Humains (MeSH), Matériaux dentaires (effets indésirables), Matériaux dentaires (pharmacocinétique), Méthacrylate bisphénol A-glycidyl (pharmacocinétique), Méthacrylates (pharmacocinétique), Peroxyde de benzoyle (pharmacocinétique), Poly(acides méthacryliques) (pharmacocinétique), Polyéthylène glycols (pharmacocinétique), Pulpe dentaire (métabolisme), Résines composites (effets indésirables), Résines composites (pharmacocinétique), Résines synthétiques (effets indésirables), Résines synthétiques (pharmacocinétique), Salive (métabolisme).
- MESH :
- effets indésirables : Matériaux dentaires, Résines composites, Résines synthétiques.
- métabolisme : Dentine, Pulpe dentaire, Salive.
- pharmacocinétique : Ciments dentaires, Matériaux dentaires, Méthacrylate bisphénol A-glycidyl, Méthacrylates, Peroxyde de benzoyle, Poly(acides méthacryliques), Polyéthylène glycols, Résines composites, Résines synthétiques.
- étiologie : Dermatite professionnelle, Eczéma de contact allergique.
- Biodisponibilité, Dent, Dentistes, Humains.
English descriptors
- KwdEn :
- Benzoyl Peroxide (pharmacokinetics), Biological Availability (MeSH), Bisphenol A-Glycidyl Methacrylate (pharmacokinetics), Composite Resins (adverse effects), Composite Resins (pharmacokinetics), Dental Cements (pharmacokinetics), Dental Materials (adverse effects), Dental Materials (pharmacokinetics), Dental Pulp (metabolism), Dentin (metabolism), Dentists (MeSH), Dermatitis, Allergic Contact (etiology), Dermatitis, Occupational (etiology), Humans (MeSH), Methacrylates (pharmacokinetics), Polyethylene Glycols (pharmacokinetics), Polymethacrylic Acids (pharmacokinetics), Resins, Synthetic (adverse effects), Resins, Synthetic (pharmacokinetics), Saliva (metabolism), Tooth (MeSH).
- MESH :
- chemical , adverse effects : Composite Resins, Dental Materials, Resins, Synthetic.
- chemical , pharmacokinetics : Benzoyl Peroxide, Bisphenol A-Glycidyl Methacrylate, Composite Resins, Dental Cements, Dental Materials, Methacrylates, Polyethylene Glycols, Polymethacrylic Acids, Resins, Synthetic.
- etiology : Dermatitis, Allergic Contact, Dermatitis, Occupational.
- metabolism : Dental Pulp, Dentin, Saliva.
- Biological Availability, Dentists, Humans, Tooth.
Abstract
Chemical components of many materials used in dental practice can move into the local biophase, where they can have beneficial or adverse effects. The strongest indirect evidence that components of resin-based materials used in dentistry can move into the biophase are the many reports of allergic dermatitis in dental personnel. Direct measurement of component release has shown that triethylene glycol dimethacrylate (TEGDMA), hydroxyethyl methacrylate (HEMA), and, in the case of some orthodontic cements, bis-glycidyl methacrylate and benzoyl peroxide can move into an aqueous medium from a range of resin-based materials which are applied to teeth as part of oral care. In the case of resin composite restorations, HEMA and TEGDMA are available in microgram quantities via the salivary surface in the minutes and hours after clinical placement and via dentin and pulp in the hours and days after placement. Fortunately, moderate thickness of dentin protects pulp tissue against local toxicity. There are no data which suggest that systemic toxicity is a risk with any of these materials. There are some case reports of allergic responses to the monomers in patients, but the incidence of such responses appears at present to be much lower than that in dental personnel.
DOI: 10.1177/10454411960070020501
PubMed: 8875031
Affiliations:
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Le document en format XML
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94143-0758</wicri:regionArea><placeName><settlement type="city">San Francisco</settlement><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Gerzina, T M" sort="Gerzina, T M" uniqKey="Gerzina T" first="T M" last="Gerzina">T M Gerzina</name></author></analytic><series><title level="j">Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists</title><idno type="ISSN">1045-4411</idno><imprint><date when="1996" type="published">1996</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Benzoyl Peroxide (pharmacokinetics)</term><term>Biological Availability (MeSH)</term><term>Bisphenol A-Glycidyl Methacrylate (pharmacokinetics)</term><term>Composite Resins (adverse effects)</term><term>Composite Resins (pharmacokinetics)</term><term>Dental Cements (pharmacokinetics)</term><term>Dental Materials (adverse effects)</term><term>Dental Materials (pharmacokinetics)</term><term>Dental Pulp (metabolism)</term><term>Dentin (metabolism)</term><term>Dentists (MeSH)</term><term>Dermatitis, Allergic Contact (etiology)</term><term>Dermatitis, Occupational (etiology)</term><term>Humans (MeSH)</term><term>Methacrylates (pharmacokinetics)</term><term>Polyethylene Glycols (pharmacokinetics)</term><term>Polymethacrylic Acids (pharmacokinetics)</term><term>Resins, Synthetic (adverse effects)</term><term>Resins, Synthetic (pharmacokinetics)</term><term>Saliva (metabolism)</term><term>Tooth (MeSH)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Biodisponibilité (MeSH)</term><term>Ciments dentaires (pharmacocinétique)</term><term>Dent (MeSH)</term><term>Dentine (métabolisme)</term><term>Dentistes (MeSH)</term><term>Dermatite professionnelle (étiologie)</term><term>Eczéma de contact allergique (étiologie)</term><term>Humains (MeSH)</term><term>Matériaux dentaires (effets indésirables)</term><term>Matériaux dentaires (pharmacocinétique)</term><term>Méthacrylate bisphénol A-glycidyl (pharmacocinétique)</term><term>Méthacrylates (pharmacocinétique)</term><term>Peroxyde de benzoyle (pharmacocinétique)</term><term>Poly(acides méthacryliques) (pharmacocinétique)</term><term>Polyéthylène glycols (pharmacocinétique)</term><term>Pulpe dentaire (métabolisme)</term><term>Résines composites (effets indésirables)</term><term>Résines composites (pharmacocinétique)</term><term>Résines synthétiques (effets indésirables)</term><term>Résines synthétiques (pharmacocinétique)</term><term>Salive (métabolisme)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Composite Resins</term><term>Dental Materials</term><term>Resins, Synthetic</term></keywords><keywords scheme="MESH" type="chemical" qualifier="pharmacokinetics" xml:lang="en"><term>Benzoyl Peroxide</term><term>Bisphenol A-Glycidyl Methacrylate</term><term>Composite Resins</term><term>Dental Cements</term><term>Dental Materials</term><term>Methacrylates</term><term>Polyethylene Glycols</term><term>Polymethacrylic Acids</term><term>Resins, Synthetic</term></keywords><keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr"><term>Matériaux dentaires</term><term>Résines composites</term><term>Résines synthétiques</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Dermatitis, Allergic Contact</term><term>Dermatitis, Occupational</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Dental Pulp</term><term>Dentin</term><term>Saliva</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Dentine</term><term>Pulpe dentaire</term><term>Salive</term></keywords><keywords scheme="MESH" qualifier="pharmacocinétique" xml:lang="fr"><term>Ciments dentaires</term><term>Matériaux dentaires</term><term>Méthacrylate bisphénol A-glycidyl</term><term>Méthacrylates</term><term>Peroxyde de benzoyle</term><term>Poly(acides méthacryliques)</term><term>Polyéthylène glycols</term><term>Résines composites</term><term>Résines synthétiques</term></keywords><keywords scheme="MESH" qualifier="étiologie" xml:lang="fr"><term>Dermatite professionnelle</term><term>Eczéma de contact allergique</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Biological Availability</term><term>Dentists</term><term>Humans</term><term>Tooth</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Biodisponibilité</term><term>Dent</term><term>Dentistes</term><term>Humains</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Chemical components of many materials used in dental practice can move into the local biophase, where they can have beneficial or adverse effects. The strongest indirect evidence that components of resin-based materials used in dentistry can move into the biophase are the many reports of allergic dermatitis in dental personnel. Direct measurement of component release has shown that triethylene glycol dimethacrylate (TEGDMA), hydroxyethyl methacrylate (HEMA), and, in the case of some orthodontic cements, bis-glycidyl methacrylate and benzoyl peroxide can move into an aqueous medium from a range of resin-based materials which are applied to teeth as part of oral care. In the case of resin composite restorations, HEMA and TEGDMA are available in microgram quantities via the salivary surface in the minutes and hours after clinical placement and via dentin and pulp in the hours and days after placement. Fortunately, moderate thickness of dentin protects pulp tissue against local toxicity. There are no data which suggest that systemic toxicity is a risk with any of these materials. There are some case reports of allergic responses to the monomers in patients, but the incidence of such responses appears at present to be much lower than that in dental personnel.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">8875031</PMID><DateCompleted><Year>1997</Year><Month>01</Month><Day>14</Day></DateCompleted><DateRevised><Year>2019</Year><Month>11</Month><Day>01</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">1045-4411</ISSN><JournalIssue CitedMedium="Print"><Volume>7</Volume><Issue>2</Issue><PubDate><Year>1996</Year></PubDate></JournalIssue><Title>Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists</Title><ISOAbbreviation>Crit Rev Oral Biol Med</ISOAbbreviation></Journal><ArticleTitle>Bioavailability of components of resin-based materials which are applied to teeth.</ArticleTitle><Pagination><MedlinePgn>172-9</MedlinePgn></Pagination><Abstract><AbstractText>Chemical components of many materials used in dental practice can move into the local biophase, where they can have beneficial or adverse effects. The strongest indirect evidence that components of resin-based materials used in dentistry can move into the biophase are the many reports of allergic dermatitis in dental personnel. Direct measurement of component release has shown that triethylene glycol dimethacrylate (TEGDMA), hydroxyethyl methacrylate (HEMA), and, in the case of some orthodontic cements, bis-glycidyl methacrylate and benzoyl peroxide can move into an aqueous medium from a range of resin-based materials which are applied to teeth as part of oral care. In the case of resin composite restorations, HEMA and TEGDMA are available in microgram quantities via the salivary surface in the minutes and hours after clinical placement and via dentin and pulp in the hours and days after placement. Fortunately, moderate thickness of dentin protects pulp tissue against local toxicity. There are no data which suggest that systemic toxicity is a risk with any of these materials. There are some case reports of allergic responses to the monomers in patients, but the incidence of such responses appears at present to be much lower than that in dental personnel.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Hume</LastName><ForeName>W R</ForeName><Initials>WR</Initials><AffiliationInfo><Affiliation>Department of Restorative Dentistry, University of California, San Francisco 94143-0758, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gerzina</LastName><ForeName>T M</ForeName><Initials>TM</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D016454">Review</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Crit Rev Oral Biol Med</MedlineTA><NlmUniqueID>9009999</NlmUniqueID><ISSNLinking>1045-4411</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D003188">Composite Resins</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D003738">Dental Cements</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D003764">Dental Materials</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D008689">Methacrylates</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D011109">Polymethacrylic Acids</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D012117">Resins, Synthetic</NameOfSubstance></Chemical><Chemical><RegistryNumber>14I47YJ5EY</RegistryNumber><NameOfSubstance UI="C020946">triethylene glycol dimethacrylate</NameOfSubstance></Chemical><Chemical><RegistryNumber>3WJQ0SDW1A</RegistryNumber><NameOfSubstance UI="D011092">Polyethylene Glycols</NameOfSubstance></Chemical><Chemical><RegistryNumber>454I75YXY0</RegistryNumber><NameOfSubstance UI="D017438">Bisphenol A-Glycidyl Methacrylate</NameOfSubstance></Chemical><Chemical><RegistryNumber>6E1I4IV47V</RegistryNumber><NameOfSubstance UI="C005044">hydroxyethyl methacrylate</NameOfSubstance></Chemical><Chemical><RegistryNumber>W9WZN9A0GM</RegistryNumber><NameOfSubstance UI="D001585">Benzoyl Peroxide</NameOfSubstance></Chemical></ChemicalList><CitationSubset>D</CitationSubset><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D001585" MajorTopicYN="N">Benzoyl Peroxide</DescriptorName><QualifierName UI="Q000493" MajorTopicYN="N">pharmacokinetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D001682" MajorTopicYN="N">Biological Availability</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D017438" MajorTopicYN="N">Bisphenol A-Glycidyl Methacrylate</DescriptorName><QualifierName UI="Q000493" MajorTopicYN="N">pharmacokinetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D003188" MajorTopicYN="N">Composite Resins</DescriptorName><QualifierName UI="Q000009" MajorTopicYN="N">adverse effects</QualifierName><QualifierName UI="Q000493" MajorTopicYN="N">pharmacokinetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D003738" MajorTopicYN="N">Dental Cements</DescriptorName><QualifierName UI="Q000493" MajorTopicYN="N">pharmacokinetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D003764" MajorTopicYN="N">Dental Materials</DescriptorName><QualifierName UI="Q000009" MajorTopicYN="N">adverse effects</QualifierName><QualifierName UI="Q000493" MajorTopicYN="Y">pharmacokinetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D003782" MajorTopicYN="N">Dental Pulp</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D003804" MajorTopicYN="N">Dentin</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D003815" MajorTopicYN="N">Dentists</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D017449" MajorTopicYN="N">Dermatitis, Allergic Contact</DescriptorName><QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D009783" MajorTopicYN="N">Dermatitis, Occupational</DescriptorName><QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008689" MajorTopicYN="N">Methacrylates</DescriptorName><QualifierName UI="Q000493" MajorTopicYN="N">pharmacokinetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011092" MajorTopicYN="N">Polyethylene Glycols</DescriptorName><QualifierName UI="Q000493" MajorTopicYN="N">pharmacokinetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011109" MajorTopicYN="N">Polymethacrylic Acids</DescriptorName><QualifierName UI="Q000493" MajorTopicYN="N">pharmacokinetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012117" MajorTopicYN="N">Resins, Synthetic</DescriptorName><QualifierName UI="Q000009" MajorTopicYN="N">adverse effects</QualifierName><QualifierName UI="Q000493" MajorTopicYN="Y">pharmacokinetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012463" MajorTopicYN="N">Saliva</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014070" MajorTopicYN="N">Tooth</DescriptorName></MeshHeading></MeshHeadingList><NumberOfReferences>93</NumberOfReferences></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>1996</Year><Month>1</Month><Day>1</Day></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>1996</Year><Month>1</Month><Day>1</Day><Hour>0</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>1996</Year><Month>1</Month><Day>1</Day><Hour>0</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">8875031</ArticleId><ArticleId IdType="doi">10.1177/10454411960070020501</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>États-Unis</li></country><region><li>Californie</li></region><settlement><li>San Francisco</li></settlement></list><tree><noCountry><name sortKey="Gerzina, T M" sort="Gerzina, T M" uniqKey="Gerzina T" first="T M" last="Gerzina">T M Gerzina</name></noCountry><country name="États-Unis"><region name="Californie"><name sortKey="Hume, W R" sort="Hume, W R" uniqKey="Hume W" first="W R" last="Hume">W R Hume</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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